Mutation Surveyor 5.2

Mutation Surveyor® is a DNA Sequencing software for the analysis of Sanger sequencing files (.ab1,.RSD,.ESD & .scf) generated by Applied Biosystems Genetic Analyzers, MegaBACE as well as Beckman CEQ electrophoresis systems. Utilizing patented anti-correlation technology Mutation Surveyor delivers excellent accuracy, sensitivity, low false positive and negative rates in the analysis of DNA variants: SNPS, insertions and deletions (Indels), Somatic Mutations in direct sequencing, medical sequencing, PCR sequencing, Mitochondria sequencing, and resequencing projects. The software also provides superior basecalling; correcting N-calls of the KB Basecaller or Variant Reporter® software packages; sequence alignment and sequence assembly, replacing such programs as DNAStar and Sequencher or SeqPilot. The package includes automated download of annotated GenBank files including amino acid sequence; de-convolution of heterozygous indels; DNA methylation detection and quantification; customizable DNA variant coding; and reporting. Mutation Surveyor has been validated for use in clinical applications by NGRL, UK and University of Pittsburgh Medical Center.